Santa Cruz Good Times

Oct 06th
Text size
  • Increase font size
  • Default font size
  • Decrease font size

Marine Organisms as Antivirals?

blog_slug_diversphoto description: Laura Sanchez and Roger Linington collect samples in Monterey Bay. Photo by Steve Clabuesch. UCSC enters into collaboration with a biopharmaceutical company to research the possibilities
A new partnership between Gilead Scientists and UC Santa Cruz will explore the possibilities of utilizing UCSC's unique library of marine natural products in a collaborative antiviral drug discovery program.

The collaboration pairs the UCSC Chemical Screening Center labs led by chemists Roger Linington and Phil Crews, which are particularly interested in drug discovery related to neglected diseases, including malaria, cholera, and African sleeping sickness, with the Gilead biopharmaceutical company, which focuses on advancements in care for life-threatening diseases worldwide. They hope to indetify compounds with potential antiviral activity in the areas of HIV and hepatitis.

In 2007, the UCSC Chemical Screening Center was established  with funding from the National Institutes of Health, the U.S. Department of State, and the California Institute for Quantitative Biomedical Research. Now, the center's natural products repository contains a total of approximately 200,000 discrete chemical entities that can be screened for potentially useful biological effects.

This project will be the first to explore use of the lab's extensive collection of natural products for antiviral potential.

Scott Lokey, director of the Chemical Screening Center and associate professor of chemistry and biochemistry, noted the benefits both sides—academics and pharmaceutical companies—bring to these kinds of collaborations, which he says are becoming increasingly more common.

"They don't have the resources to develop a natural products program on their own, and we don't have the resources to take an interesting compound and move it into clinical development, so it's a win-win," he stated on UCSC's website, "Having a partnership with a pharmaceutical company means that something we discover here could translate into a clinically useful drug, and that's really exciting."

photo description: Laura Sanchez and Roger Linington collect samples in Monterey Bay. Photo by Steve Clabuesch.


Comments (0)Add Comment

Write comment
smaller | bigger


Share this on your social networks

Bookmark and Share

Share this

Bookmark and Share


Making a Scene

As it celebrates its 30th year, Santa Cruz County’s Open Studios is one of the most successful in the country—and a make-or-break event for many local artists


A Ritual & Initiation

The Pope has come and gone, but his loving presence ignited new hope and goodness in many. While he was in NYC, China’s ruler arrived in Washington D.C. East (China) and West (Rome), meeting in the middle, under Libra, balancing sign of Right Relations. The Pope arrived at Fall Equinox. Things initiated at Fall Equinox are birthed at Winter Solstice. The Pope’s presence was a ritual, an initiation rite—like the Dalai Lama’s visits—offering prayers, teachings and blessings. Rituals anchor God’s plan into the world, initiating us to new realities, new rules. The Pope’s presence brings forth the Soul of the United States, its light piercing the veils of materialism. The Pope’s visit changed things. New questions arise, new reasons for living. A new wave of emerging life fills the air. Like a cocoon shifting, wings becoming visible. The winds are different now. Calling us to higher vision, moral values, virtues that reaffirm and offer hope for humanity. A changing of the guard has occurred. Appropriately, this is the week of the Jewish Festival of Sukkoth (’til Oct. 4), when we build temporary homes (little huts in nature), entering into a harvest of prayer and thanksgiving, understanding our fragile and impermanent existences. We are summoned to reflect upon our lives, our humanity, our nature, our spirit and each other. Offering gratitude, becoming a magnet for others. We observe. We see the needs. We love more.


The New Tech Nexus

Community leaders in science and technology unite to form web-based networking program


Film, Times & Events: Week of October 2

Santa Cruz area movie theaters >
Sign up for Good Times weekly newsletter
Get the latest news, events

RSS Feed Burner

 Subscribe in a reader

Latest Comments


Extra Pop

Assembly’s pop-up space goes into regular rotation, Cabrillo wine dinner, and a visit to Mozaic


What’s your biggest pet peeve?

When people say they’re “going down” somewhere, and they’re actually traveling north. Julia Ragen, Santa Cruz, Psychologist


Downhill Cellars

An easy-drinking Chardonnay from Downhill Cellars


Gary’s Old Fashioned Snappy Dogs

Where to find the best hot dogs in Santa Cruz